Description

Machine Overview: The Rapid Mixer Granulator (RMG) is an advanced, high-speed granulation machine designed to achieve fast, efficient, and uniform mixing of dry powders and the wet granulation process in a single step. It plays a crucial role in the pharmaceutical, food, nutraceutical, chemical, and cosmetic industries, ensuring high-quality granules essential for further processing, such as tablet compression and capsule filling. Built following cGMP (Current Good Manufacturing Practice) guidelines, our RMG ensures compliance with industry standards, delivering superior product consistency, safety, and efficiency. It is available in various capacities to meet the needs of small-scale R&D, pilot production, and large-scale manufacturing. Key Components: 1) Mixing Bowl – Constructed from SS 316L stainless steel, ensuring durability and hygiene compliance. 2) Impeller & Chopper – High-speed stainless-steel blades that ensure efficient mixing and controlled granule formation. 3) Spray Nozzle System – For precise addition of the binder solution during wet granulation. 4) Air Purging System – Prevents contamination by keeping the granulation zone dust-free. 5) Discharge Port with Pneumatic Control – Ensures smooth, controlled granule discharge with minimal material loss. 6) Control Panel (PLC/SCADA-Based) – User-friendly interface for monitoring and controlling granulation parameters. 7) GMP-Compliant Filters & Seals – Prevent cross-contamination and maintain process integrity. 8) CIP (Clean-in-Place) System – Ensures easy cleaning and minimal downtime. Operating Principle: The Rapid Mixer Granulator (RMG) follows a high-shear mixing and wet granulation process, which consists of: 1) Ingredient Loading – Dry powders are fed into the mixing bowl manually or through a vacuum transfer system. 2) Mixing Stage – The high-speed impeller ensures uniform blending of powders by lifting, tumbling, and dispersing them. 3) Binder Addition & Granulation – A binder solution is added through the spray nozzle system while the chopper blade breaks lumps and promotes granule formation. 4) Granule Discharge – Once the desired granule size is achieved, the batch is discharged through the outlet for further processing in a Fluid Bed Dryer (FBD) or Tray Dryer. The result is uniformly sized, free-flowing granules that improve tablet compression, enhance dissolution, and minimize production variations. Applications Across Various Industries: Pharmaceutical Industry: Granulation of API (Active Pharmaceutical Ingredients) and excipients. Preparation of wet granules for tablets and capsules. Ensures batch-to-batch consistency for high-quality formulations. Food & Nutraceutical Industry: Granulation of protein powders, dietary supplements, and vitamin premixes. Production of food additives, flavor enhancers, and beverage mix powders. Chemical Industry: Granulation of catalysts, specialty chemicals, and agrochemical formulations. Enhances flow properties and reduces dust formation. Cosmetic Industry: Mixing and granulation of powdered ingredients for skincare and personal care products. Ensures uniform distribution of active ingredients for better product performance. Key Benefits: 1) High-Speed & Efficient Processing – Rapid mixing and granulation in a single step, reducing overall processing time. 2) Uniform Granule Formation – Achieves consistent particle size distribution, improving downstream processing. 3) GMP & cGMP Compliant – Meets global regulatory standards for safe, hygienic manufacturing. 4) Automated PLC Control – Provides precise control over mixing time, impeller/chopper speed, and binder addition. 5) Scalable Design – Available in R&D, pilot-scale, and commercial production models. 6) Minimal Material Loss & Dust-Free Operation – Maximizes yield while ensuring a cleaner work environment. 7) Energy-Efficient & Cost-Effective – Optimized for lower energy consumption and increased productivity. 8) Easy Cleaning & Maintenance – CIP (Clean-in-Place) system for minimal downtime and faster changeovers. For more details, please visit: www.ramashary.com