After access cavity opening, localisation and coronal pre-enlargement, the canal can be penetrated with manual or rotary files to allow debridement of the canal and establish glide path. NiTi rotary instruments allow a quicker and more reliable glide path preparation. Pro Glide file helps in establishment of predictable glide path and decreases chairtime with reduced risk of file breakage. Most complex root canal anatomy can be securely negotiated thanks to its superior flexibility, while its strength prevents cyclic fatigue and breakage.